This study examined the prevalence severity and correlates of nonmedical prescription stimulant use (NPSU) among youth in the Emergency Department (ED). use risk factors compared to those with no NPSU. Also those with moderate/severe NPSU were more likely to report dating violence and nonmedical use of opioids or sedatives and less likely to use marijuana compared to those with moderate NPSU. Healthcare setting screening and intervention efforts should consider NPSU concomitant with other substance use and explore the association of dating violence with NPSU. < .001) and were more likely to be male (28.7%) than female (21.4%; χ2 = 40.88 < .001). Patients who refused participation and screened patients did not significantly differ on gender or age distribution. The average age of the entire study sample was 17.5 years (standard deviation (SD) 2.0) 2542 (57.9%) were female and 3185 (72.6%) identified as Caucasian. 3.2 Non-medical Prescription Stimulant Use Characteristics In this sample 365 (8.3%) reported NPSU in the past year and of those the majority (n=257 83 reported LY 2874455 NPSU in the past 3 months. Based on NM-ASSIST scores for NPSU over the past 3 months 189 participants were classified as mild risk. Few participants fell into the high risk range (n = 8). For further analyses the high-risk patients were combined with those in the moderate risk range (n = 168) for a total of 176 participants in the LY 2874455 moderate/high risk range for NPSU. Among the participants with any NPSU in the past 3 months (n=257) 55.6% (n = 143) used less than monthly 14.8% (n=38) reported monthly use and 30.0% (n=76) reported weekly or daily use. Also 21.8% (n=56) had a strong desire or urge to misuse prescription stimulants on a weekly to daily basis and LY 2874455 8.6% (n=22) had weekly or daily health social legal or financial problems secondary to NPSU. A LY 2874455 total of 12.0% (n=31) had failed to do what was normally expected of them in the past 3 months because of NPSU 12.5% (n=32) noted that a friend or relative had expressed concern about their NPSU and 9.7% (n=25) reported failed attempts to cut down control or stop misuse of prescription stimulants. 3.3 Bivariate Results Table 1 displays results of the bivariate associations across the three groups. Patients with any NPSU tended to be older (F-value = 21.08 df =2 p <0.0001) and were more likely to identify as Caucasian (x2 = 43.47 df =4 p <0.0001) compared to those with no NPSU. Patients with no NPSU were more likely to be in school (x2 = 19.79 df = 2 p<0.0001) and less likely to have failing grades or have dropped out of school (x2 = 15.89 df = 2 p = 0.0004) compared to those with mild NPSU or moderate/severe NPSU. Table 1 Demographics and Risk Factors for Past Year Non-medical Prescription Stimulant Use All risk factors including violence and substance use were significantly related to both mild NPSU and moderate/severe NPSU compared to no NPSU. Most patients were discharged from the ED and there was no difference in rates of discharge from the ED across the three groups (x2 = 1.28 df = 2 p = 0.53). Patients with moderate/severe NPSU were more likely to have been to the ED in the past 12 months (x2 = 5.67 df = LY 2874455 2 p = 0.02) compared to other groups. Also while the absolute numbers were small participants with mild or moderate/severe NPSU were more likely to use any drugs within 6 hours of the ED visit (x2 =33.71 df = 1 p <0.0001) and more likely to report nonmedical prescription drug use within six hours of the ED visit (x2 = 399.29 df = 1 p <0.0001). 3.4 Multinomial Regression Analysis Results The results of the multinomial model are presented in Table 2. Compared to participants without NPSU participants with mild NPSU (aOR 3.57 95 Mouse monoclonal to NKX2.5 CI 1.69-7.75) and moderate/severe NPSU (aOR 4.69 95 CI 2.08-10.59) were more likely to identify as Caucasian. However there was no difference in race when comparing those with mild NPSU to those with moderate/severe NPSU. Female participants had decreased odds of moderate/severe NPSU (aOR 0.69 95 CI 0.49-0.97) compared to those without NPSU but there was no difference between those with mild NPSU and no NPSU. Table 2 Multinomial Regression Predicting Risk Category for Nonmedical Prescription Stimulant Use (NMSU). Participants with mild NPSU had higher odds of.